Refined. Unless you are pure strength, otherwise refined is where you want to go with this. It could also be argued that jack of all trades builds at 40/40; 40/40 might consider using a strong elemental gem, like a dark crystal, as I'm told it scales great down the board. I'm at 70/70 (refined obviously) and only +9 and I'm at a bit over 600 total damage. At +10 refined, with your favorite resin, and this is definitely to be considered one of the best weapons in the game for people that know how to wield it.