Arguably the hardest fight in the game. To make the fight a little easier talk to him with your weakest member and start attacking his servants, they will then start a fight without involving him, making the actual fight with the demon easier.

To avoid him chugging big annoying potions, just buy them off him before the fight. Leave him with low potions or Food that doesnt really do anything and he will chug These instead.

This boss can be cheesed. I killed him in demon form after Malady spoiler stuff. I beat him at lvl 18, had 2 mages in the squad. I killed all the nurses first, had to do corpse dragging(many rez scrolls were used here due to boss aggroing as I killed nurses 1 by 1 and boss also simply 1 shot my Lohse, rez the mages with squad member standing by outside the mansion...) Anyways, I only used 4 skills, 1. Meteor shower 2. Hail Strike 3. Thunder Storm 4. Dazing Bolt These can damage the boss without putting you in combat due to ridiculous range. Boss will be constantly patrolling the house, so bow cheese doesn't work. But, what happens with the spells is they alter the ground condition. When floor gets frozen or electrified, boss will try to stay in dry surface and run to corner. For me, demon retreated to the room next to cellar, so I kept him in the room by continuously raining down hail strike, thunder storm, meteor shower. You will start to run out of source if you are not standing on source pool. (Use Terrain Transmutation to bring a source pool so you can spam source skills) Best fight in the game for me, because this strategy made Divinity 2 an action RPG for me LOL

Me and my friends did this through a coordinated magic attack, only normal difficulty he has 2k magic shield while not in demon mode. I used artillery plant poison attack for 5k damage, friends lava slug did lazer ray for 3k more, and bow friend finished it with a 1.5k pierce arrow. Your best bet is simply killing him before he transforms. If an ally has high enough initiative to go before him, and you can do a huge coordinated attack, magic or physical (though he has significantly less magic shield), you are set.

On honour mode he will possess/kill lose on his 2nd turn and give you an instant game over - this is neglected in any online guide I read before the fight.

I just dropped him in one turn and only did 4400 earth damage to do it. I don't understand how

For my play though I was playing as Loseh and didn't want to kill all the people so I went into the fight without weakening Adramahlihk. So I had to take him down in one round. What I did was take my tank who has the highest armor, boost that armor further with different spells and scrolls before the fight, made sure the tank was standing right by Adramahlihk when the fright was starting to him him as much ap as possible, then used Reactive Armour and took out all of his armor and a nice chunk of his health while I was at it. It was pretty simple once his armor was gone to finish him off.

I'm playing as Ifan and have Lohse in my party. I've been playing the "I'll save you card", but wanted her to pull out a crazy god combo to take down her demon. I also dragged her out of the demonic plane before she could kill off her fellow captives, so this guy was gonna be beefy. I was playing her as an elemental (maxed out poly for higher int, 3-5 in areo, hydro, geo, pyro, necro), but respeced into aero and geo specifically (still max poly), dropped memory to the minimum and put left over points in wits. I had another party member sneak up and check the weaknesses, so justified it as Lohse refocusing her magic on what would win her the battle. She confronts the doc, while Beast buffs her with some magic armor and clear-minded. Sebille goes off to hide, and Ifan just glares. Demon comes out, Lohse sips a lovely green tea. She goes in with Apotheosis -> Pyroclastic -> Thunderstorm, rest of the crew made an incarnate, made a chicken and threw some lame attempts at magic (battlemage who hits for physical damage and uses aero/hydro for CC). The goons are all stunned (or a chicken), and doctor drama-llama spends the next turn charging up(?), so back to us. Lohse throws Closed Circuit -> Acid Spores -> Dazing Bolt, eliminating Adram's armour and shocking him. Trusting her fellow adventures to stun him and give her a chance to finish him off, she Skin Grafts. Her friends protect her from both the demon and his lackeys, with calculated shots, spells and slices to keep them down. Lohse summons the last of her near-godly power, and crushes her oppressor with another Pyroclatic Eruption. She sends another Thunderstorm after the last living demon, finishing him off with a Dazing Bolt. The party, with only a few dings in their armour to show for the battle, rejoices that she's finally free of her tormentor. All in all, it was a cheesy way to beat what appears to be an incredibly difficult boss under normal circumstances. That being said, it fit in with the way I was progressing the characters, and felt absolutely amazing to pull off. The fact that cheesing fights is actually enjoyable is one of the coolest things about this game!

Teleport the receptionist nurse outside the front door, this will aggro 3 of the nurses and not the doctor so you can cheese them. For the actual doctor fight, lure him and the remaining nurses to the front door and spam area attacks, and taunt is very useful here to mitigate o.h.k.o while burning his 14k armour. Once his armour is down, it's all down to stun locks.