You can actually bypass some areas whithout even using glitches.
When you're in the village of smiles you don't need to kill the queen, just gor right from the sanctuary to acces the watching woods.
Again, no need to take down the alchemist, just go to the bottom right of the woods and leap to go fight the cyclop.
If you killed the cyclop you can bypass the false jester using the key dropped by the cyclop by taking the door below the boss area.
After you killed the wyrm and got the shadow flip brand, go directly to the right from the sanctuary in the red hall to access the dome of the forgotten.
Once you finished the dome go right from the dome to the ziggourat, since only the hardlight and shadowflip brands are needed to acces the dried king
As soon as you've killed the king, use the dart brand to go to pitch woods from the sanctuary at the far beach. You will only need to get through the "unicorn" to access siam lake.
From there, I don't think you can skip any more areas, but the crypt of the dead gods can be rushed quickly by staying near the right wall and falling directly from the entrance to near the shrine next to the boss.
Using this road you avoid the fights against the queen of smiles, the mad alchemist, the false jester, the tree of men, the disembollowed husk, that stench most foul, the bloodless prince and the coveted (not to mention the bosses who are generally labelled as optional : Murdiella Mal, Carsejaw the cruel, Ronin Cran and the forgotten king), but you risk having a really low level when fighting against the last bosses (which might not be a problem if you're part of the order of the betrayer and can spam black magic+flask of defilement)
I think you can also skip the fight against the sodden knight by leaping from the platform above the shrine in the festering banquet, not sure if the devs intended that though.